Programmed cell death in sepsis in Balkan nephropathy
نویسندگان
چکیده
منابع مشابه
Programmed cell death in sepsis in balkan nephropathy.
Sepsis is defined as a suspected or proven infection in the systemic inflammatory response syndrome (SIRS) . From the beginning of a systemic infection and over sepsis peaks of immune-mediators characteristic of SIRS and for the compensatory anti-inflammatory response syndrome (CARS) may be seen in sequence or in parallel 2 that enlighten the reason why broad investigation of inflammatory bioma...
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INTRODUCTION A major pathophysiologic mechanism in sepsis is impaired host immunity which results in failure to eradicate invading pathogens and increased susceptibility to secondary infections. Although many immunosuppressive mechanisms exist, increased expression of the inhibitory receptor programmed cell death 1 (PD-1) and its ligand (PD-L1) are thought to play key roles. The newly recognize...
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OBJECTIVE Sepsis remains a leading cause of death in many Intensive Care Units worldwide. Immunosuppression has been a primary focus of sepsis research as a key pathophysiological mechanism. Given the important role of the negative costimulatory molecules programmed cell death-1 (PD-1) and programmed death-ligand 1 (PD-L1) in the occurrence of immunosuppression during sepsis, we reviewed litera...
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Programmed cell death (PCD) of Dictyostelium discoideum cells was triggered precisely and studied quantitatively in an in vitro system involving differentiation without morphogenesis. In temporal succession after the triggering of differentiation, PCD included first an irreversible step leading to the inability to regrow at 8 hours. At 12 hours, massive vacuolisation was best evidenced by confo...
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ژورنال
عنوان ژورنال: Military Medical and Pharmaceutical Journal of Serbia
سال: 2013
ISSN: 0042-8450,2406-0720
DOI: 10.2298/vsp111101045s